BEIJING, March 24 (Xinhuanet)
-- A new test that analyzes microRNAs can tell doctors the source
of some mysterious cancers and help provide a short-cut for
treating them, according to media reports quoting researchers in the Nature
Biotechnology Monday.¡¡
Nitzan Rosenfeld of Israel-based
Rosetta Genomics and colleagues said their
test used microRNAs, a type of genetic material that regulates genes and known
to be involved in cancer, as effective biomarkers to identify where in the body
a tumor started.
Researchers used the specific chemotherapies to
identify tumors that had spread in the body from unknown sources -- a type of
cancer known as "cancer of unknown primary" or CUP.
After examining 400 samples of 22 different tumor
tissues and metastases, they identified the source in two-thirds of cases, they
reported.
Most cancers are named according to the place they
first develop. But there is a group of patients with whom you can't find a
primary tumor. It either acquires the ability to metastasize so early in
development that primary doesn't develop. Or the primary never exists. Being
able to identify the primary origin of a cancer is key to treating it.
(Agencies)